Description

Aminopeptidase N Inhibitor CAS NO 596108-59-7 is a potent and selective small molecule inhibitor of the enzyme aminopeptidase N (APN/CD13). This compound is a critical research tool for investigating the role of APN in biological processes, as it effectively modulates its enzymatic activity. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in oncology, immunology, and inflammation studies.

Application

• Biochemical Research: A fundamental tool for in vitro and cell-based assays to study the function and inhibition kinetics of aminopeptidase N (CD13).
• Oncology Research: Used to investigate the role of APN/CD13 in tumor angiogenesis, metastasis, and cell proliferation, supporting the development of novel anti-cancer therapeutics.
• Immunology & Inflammation Studies: Applied in research models to explore the involvement of APN in immune cell regulation and inflammatory pathways.
• Enzyme Mechanism Studies: Serves as a reference standard for characterizing enzyme-substrate interactions and inhibitor binding sites.
• High-Throughput Screening (HTS): Utilized as a control compound in drug discovery campaigns targeting metalloproteases.
• Preclinical Development: Supports proof-of-concept studies for therapeutic candidates targeting APN-related diseases.

Basic Information

Product Name	Aminopeptidase N Inhibitor
CAS No.	596108-59-7
Molecular Formula	C23H23N5O3
Molecular Weight	417.46 g/mol
Synonyms	Bestatin Derivative; APN Inhibitor; CD13 Inhibitor; (2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]pentanediamide; Phenylalanine-based APN Inhibitor
EINECS	Contact for details

Quality Control

Our Aminopeptidase N Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identification (by IR and MS), and other critical parameters is provided with every shipment to guarantee reproducible research results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.