Description

5-Chlorosulfonyl-Nicotinic Acid Methyl Ester is a versatile and high-purity chemical intermediate essential for advanced organic synthesis. Its reactive chlorosulfonyl and ester functional groups make it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for nicotinic acid derivatives and sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Organic Synthesis Building Block: Employed in research and development for creating complex heterocyclic compounds and functionalized pyridine derivatives.
• Material Science Research: Serves as a monomer or modifying agent in the development of specialty polymers and advanced functional materials.
• Chemical Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-Chlorosulfonyl-Nicotinic Acid Methyl Ester
CAS No.	594839-14-2
Molecular Formula	C7H6ClNO4S
Molecular Weight	235.64 g/mol
Synonyms	Methyl 5-(chlorosulfonyl)nicotinate; 5-(Chlorosulfonyl)nicotinic acid methyl ester; Nicotinic acid, 5-(chlorosulfonyl)-, methyl ester; Methyl 5-chlorosulfonylpyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-(chlorosulfonyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 5-Chlorosulfonyl-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.