Description

1H-Indole,5,7-Difluoro-2,3-Dihydro-2-(3-Pyridinyl)-(9Ci) is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique indole-pyridine fused structure, which serves as a privileged scaffold for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and active ingredients. Its specific substitution pattern makes it a critical intermediate for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probe: Utilized in medicinal chemistry to develop molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.
• Fluorescent Dye Synthesis: Acts as a precursor for developing specialized fluorophores and imaging agents used in biochemical assays and diagnostics.

Basic Information

Product Name	1H-Indole,5,7-Difluoro-2,3-Dihydro-2-(3-Pyridinyl)-(9Ci)
CAS No.	591721-08-3
Molecular Formula	C14H10F2N2
Molecular Weight	244.24 g/mol
Synonyms	5,7-Difluoro-2-(pyridin-3-yl)-2,3-dihydro-1H-indole; 2-(3-Pyridinyl)-5,7-difluoro-2,3-dihydro-1H-indole; 5,7-Difluoro-2-(3-pyridyl)indoline; 3-(5,7-Difluoro-2,3-dihydro-1H-indol-2-yl)pyridine; 591721-08-3 (CAS); Difluorinated Indole-Pyridine Hybrid; Indoline, 5,7-difluoro-2-(3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 1H-Indole,5,7-Difluoro-2,3-Dihydro-2-(3-Pyridinyl)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.