Description

Methyl 3-Trifluoro-2-Pyridinecarboxylate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its trifluoromethyl and ester functionalities make it an essential intermediate for introducing fluorine atoms into complex molecular architectures, which is a key strategy for modulating the physicochemical and biological properties of target compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic compounds and fluorinated analogs.
• Ligand and Catalyst Development: Utilized in the synthesis of novel pyridine-based ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 3-Trifluoro-2-Pyridinecarboxylate
CAS No.	588702-69-6
Molecular Formula	C8H6F3NO2
Molecular Weight	205.13 g/mol
Synonyms	Methyl 3-(trifluoromethyl)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-(trifluoromethyl)-, methyl ester; 3-Trifluoromethyl-2-pyridinecarboxylic acid methyl ester; Methyl 3-trifluoromethylpicolinate; 3-(Trifluoromethyl)picolinic acid methyl ester; Methyl 3-trifluoromethyl-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Trifluoro-2-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.