Description

1-[6-(Trifluoromethyl)Pyridin-2-Yl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-pyridine hybrid structure with a trifluoromethyl substituent. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a sophisticated ligand or scaffold in organometallic chemistry and catalysis for fine chemical production.
• Chemical Biology Research: Employed as a molecular probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1-[6-(Trifluoromethyl)Pyridin-2-Yl]Piperidine-4-Carboxylic Acid
CAS No.	582325-39-1
Molecular Formula	C12H13F3N2O2
Molecular Weight	274.24 g/mol
Synonyms	2-(4-Carboxypiperidin-1-yl)-6-(trifluoromethyl)pyridine; Piperidine-4-carboxylic acid, 1-[6-(trifluoromethyl)-2-pyridinyl]-; 6-(Trifluoromethyl)-2-(4-piperidinecarboxylic acid)pyridine; 1-(6-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid; 2-(1-Piperidinecarboxylic acid-4-yl)-6-trifluoromethylpyridine; 582325-39-1; 1-(6-Trifluoromethyl-2-pyridyl)piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[6-(Trifluoromethyl)Pyridin-2-Yl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.