Description

6-(4-Fluoro-Phenyl)-2-Methyl-Nicotinic Acid is a high-purity, multi-functional organic intermediate with significant utility in advanced chemical synthesis. This compound is valued for its structural motif, which is integral to the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorinated phenyl group for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP guidelines.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	6-(4-Fluoro-Phenyl)-2-Methyl-Nicotinic Acid
CAS No.	582325-06-2
Molecular Formula	C13H10FNO2
Molecular Weight	231.22 g/mol
Synonyms	2-Methyl-6-(4-fluorophenyl)nicotinic acid; 6-(4-Fluorophenyl)-2-methylpyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-(4-fluorophenyl)-2-methyl-; 582325-06-2; 6-(p-Fluorophenyl)-2-methylnicotinic acid; 2-Methyl-6-(p-fluorophenyl)nicotinic acid; 6-(4-Fluorophenyl)-2-methyl-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(4-Fluoro-Phenyl)-2-Methyl-Nicotinic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our quality systems support development under ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.