Description

n-Methyl-1-[4-(Trifluoromethyl)Phenyl]Ethylamine is a high-purity, versatile chiral amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a basic amine group and a lipophilic, electron-withdrawing trifluoromethylphenyl moiety, enabling precise modulation of molecular properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for creating novel active ingredients, particularly in the development of receptor-targeted molecules and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require specific fluorinated aromatic components.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes used in biochemical assays and diagnostic research.

Basic Information

Product Name	n-Methyl-1-[4-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	574731-05-8
Molecular Formula	C10H12F3N
Molecular Weight	203.20 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]ethanamine, N-methyl-; α-Methyl-4-(trifluoromethyl)benzeneethanamine; N-Methyl-1-(4-trifluoromethylphenyl)ethylamine; (RS)-N-Methyl-1-[4-(trifluoromethyl)phenyl]ethylamine; 1-(4-Trifluoromethylphenyl)ethyl-methyl-amine; N-Methyl-α-methyl-4-(trifluoromethyl)benzeneethanamine
EINECS	Contact for details

Quality Control

Our n-Methyl-1-[4-(Trifluoromethyl)Phenyl]Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity determination, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (Specific enantiomer available)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.