Description

15-Deoxy-δ12,14-Prostaglandin A1 is a specialized prostaglandin analog, a member of the cyclopentenone prostaglandin (CyPG) class, known for its potent biological activity. This compound is a critical research tool and potential synthetic intermediate for investigating cellular stress responses, inflammation, and apoptosis pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for drug discovery and advanced biochemical studies.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of the Nrf2/ARE pathway, oxidative stress, and anti-inflammatory mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the synthesis of novel therapeutic agents targeting inflammation and cancer.
• Cell Signaling Studies: Employed to investigate the role of cyclopentenone prostaglandins in apoptosis (programmed cell death) and cellular protection.
• Enzyme Inhibition Assays: Acts as a substrate or inhibitor in enzymatic studies related to prostaglandin metabolism and signaling cascades.
• Academic Research: Fundamental research tool in university and institutional labs for exploring biochemistry and molecular pharmacology.

Basic Information

Product Name	15-Deoxy-δ12,14-Prostaglandin A1
CAS No.	573951-20-9
Molecular Formula	C20H30O4
Molecular Weight	334.45 g/mol
Synonyms	15-Deoxy-δ12,14-Prostaglandin A1; 15-Deoxy-δ12,14-PGA1; 15d-δ12,14-PGA1; 15-Deoxy-δ12,14-PGJ1 precursor; CyPG analog; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid derivative
EINECS	Contact for details

Quality Control

Our 15-Deoxy-δ12,14-Prostaglandin A1 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting research reproducibility and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.