Description

5-Nitro-3-Trifluoromethylpyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its nitro, trifluoromethyl, and cyano substituents. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Precursor: Serves as a building block for functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probe Development: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated pyridine chemistry.

Basic Information

Product Name	5-Nitro-3-Trifluoromethylpyridine-2-Carbonitrile
CAS No.	573762-57-9
Molecular Formula	C7H2F3N3O2
Molecular Weight	217.11 g/mol
Synonyms	2-Cyano-5-nitro-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-5-nitropyridine-2-carbonitrile; 5-Nitro-3-(trifluoromethyl)picolinonitrile; 2-Pyridinecarbonitrile, 5-nitro-3-(trifluoromethyl)-; 5-Nitro-3-trifluoromethyl-2-cyanopyridine
EINECS	Contact for details

Quality Control

Our 5-Nitro-3-Trifluoromethylpyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.