Description

4,5-Difluoro-1-Benzofuran-7-Carbaldehyde is a high-purity, multi-functional benzofuran derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique difluorinated benzofuran scaffold, which is instrumental in modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the difluoro motif can enhance metabolic stability and bioavailability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Chemical Biology Probe: Utilized as a scaffold for creating fluorescent tags, molecular probes, and other tools for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for custom synthesis services and scale-up production under cGMP conditions for clinical trial material.

Basic Information

Product Name	4,5-Difluoro-1-Benzofuran-7-Carbaldehyde
CAS No.	555155-10-7
Molecular Formula	C9H4F2O2
Molecular Weight	182.13 g/mol
Synonyms	7-Formyl-4,5-difluorobenzofuran; 4,5-Difluorobenzofuran-7-carboxaldehyde; 1-Benzofuran-7-carboxaldehyde, 4,5-difluoro-; 555155-10-7; 4,5-Difluoro-7-formylbenzofuran; 4,5-Difluoro-1-benzofuran-7-carboxaldehyde; 4,5-Difluorobenzofuran-7-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4,5-Difluoro-1-Benzofuran-7-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Our standard quality commitment includes HPLC purity ≥97% (typical), with detailed impurity profiling available. Certificates of Analysis (COA) with full chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, MS) are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere for long-term storage). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.