Description

Trifluoroethan-1-One) Dihydrochloride is a high-purity fluorinated organic salt, a key building block in advanced chemical synthesis. Its value lies in providing a reactive trifluoroacetyl equivalent under controlled conditions, enabling the introduction of fluorine atoms to enhance molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoroacetyl group for metabolic stability or bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where fluorination improves efficacy and environmental profile.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the CF3CO- moiety into complex organic molecules in research and process chemistry.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with tailored surface properties and stability.
• Fluorination Chemistry: Acts as a controlled source of fluorine in synthetic pathways for creating compounds with enhanced lipophilicity and biological activity.

Basic Information

Product Name	Trifluoroethan-1-One) Dihydrochloride
CAS No.	548488-50-2
Molecular Formula	C2H3Cl2F3O
Molecular Weight	178.95 g/mol
Synonyms	1,1,1-Trifluoroacetone Dihydrochloride; Trifluoroacetone Dihydrochloride; 1,1,1-Trifluoro-2-propanone Dihydrochloride; 3,3,3-Trifluoro-2-oxopropane Dihydrochloride; TFADHCl; Trifluoroacetyl Methyl Dihydrochloride; Acetone, 1,1,1-trifluoro-, dihydrochloride
EINECS	Contact for details

Quality Control

Our Trifluoroethan-1-One) Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 103.0 %
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.