Description

2-Methyl-6-(Trifluoromethyl)Nicotinaldehyde, 97% is a high-purity, functionalized nicotinaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the aldehyde group combined with the electron-withdrawing and steric properties imparted by the trifluoromethyl and methyl substituents on the pyridine ring. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional organic materials, such as liquid crystals and organic semiconductors, due to its rigid, aromatic structure.
• Chemical Biology Probes: Utilized to develop molecular probes and fluorescent tags for studying biological processes.

Basic Information

Product Name	2-Methyl-6-(Trifluoromethyl)Nicotinaldehyde, 97%
CAS No.	545394-83-0
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	6-(Trifluoromethyl)-2-picolinaldehyde; 2-Methyl-6-(trifluoromethyl)pyridine-3-carboxaldehyde; 3-Formyl-2-methyl-6-(trifluoromethyl)pyridine; 2-Methyl-6-trifluoromethylnicotinaldehyde; 2-Methyl-6-(trifluoromethyl)-3-pyridinecarboxaldehyde; 545394-83-0; 6-(Trifluoromethyl)-2-methyl-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-6-(Trifluoromethyl)Nicotinaldehyde is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.