Description

Pyridin-2-Yl-Methanesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, enabling the efficient introduction of the pyridinylmethanesulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the sulfonamide group is a common pharmacophore.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying proteins and other biomolecules to study biological pathways.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Pyridin-2-Yl-Methanesulfonyl Chloride
CAS No.	540523-41-9
Molecular Formula	C7H8ClNO2S
Molecular Weight	205.66 g/mol
Synonyms	2-Pyridylmethanesulfonyl chloride; (Pyridin-2-yl)methanesulfonyl chloride; 2-Pyridinemethanesulfonyl chloride; 2-Picolylsulfonyl chloride; α-Pyridylmethanesulfonyl chloride; P2MSC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Pyridin-2-Yl-Methanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment. We adhere to relevant industry standards for fine chemical intermediates to support your research and development and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.