Description

Isoquinoline, 4-Fluoro-1,2,3,4-Tetrahydro- (9Ci) is a fluorinated tetrahydroisoquinoline derivative, a versatile and valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical sector where the tetrahydroisoquinoline scaffold is prevalent. It is primarily needed by research chemists and process development scientists in pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• As a pharmaceutical intermediate in the synthesis of potential drug candidates targeting neurological disorders, cancer, and cardiovascular diseases.
• Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis due to its modifiable core structure.
• Serves as a key precursor for the development of fluorinated bioactive compounds, leveraging the fluorine atom for improved metabolic stability and membrane permeability.
• Potential use in agrochemical research for creating new active ingredients with enhanced properties.
• Application in material science as a building block for specialty chemicals, ligands, or functional polymers.
• Used in academic and industrial R&D for methodological development in organic synthesis and fluorination chemistry.

Basic Information

Product Name	Isoquinoline, 4-Fluoro-1,2,3,4-Tetrahydro- (9Ci)
CAS No.	537033-79-7
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	4-Fluoro-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-4-fluoroisoquinoline; 4-Fluoro-3,4-dihydro-1H-isoquinoline; 4-Fluoro-1,2,3,4-tetrahydroisoquinoline; 4-Fluoro-THIQ; 4-F-THIQ; 4-Fluoro-1,2,3,4-tetrahydro-isoquinoline
EINECS	Contact for details

Quality Control

Our Isoquinoline, 4-Fluoro-1,2,3,4-Tetrahydro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.