Description

1-(Phenylsulfonyl)Indole-3-Sulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling the controlled introduction of the indole-sulfonyl pharmacophore into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Building block for creating new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Used in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Serves as a versatile linker or labeling reagent in probe and conjugate synthesis for biological studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke client projects.

Basic Information

Product Name	1-(Phenylsulfonyl)Indole-3-Sulfonyl Chloride
CAS No.	535930-73-5
Molecular Formula	C14H10ClNO4S2
Molecular Weight	355.81 g/mol
Synonyms	1-(Benzenesulfonyl)-1H-indole-3-sulfonyl chloride; 1H-Indole-3-sulfonyl chloride, 1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)indole-3-sulfonyl chloride; Indole-3-sulfonyl chloride, 1-(phenylsulfonyl)-; 1-Benzenesulfonylindole-3-sulfonyl Chloride; PSISC; 1-PSI-3-SC
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)Indole-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.