Description

2-(2,4-Difluoro-Phenyl)-Pyrrolidine is a high-value fluorinated pyrrolidine derivative, a crucial building block in modern organic synthesis. Its molecular structure, featuring both a pyrrolidine ring and a difluorophenyl group, makes it an essential intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique electronic or optical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic agents in biochemical research.

Basic Information

Product Name	2-(2,4-Difluoro-Phenyl)-Pyrrolidine
CAS No.	524674-05-3
Molecular Formula	C10H11F2N
Molecular Weight	183.20 g/mol
Synonyms	2-(2,4-Difluorophenyl)pyrrolidine; 2-(2,4-Difluorophenyl)-1-pyrrolidine; Pyrrolidine, 2-(2,4-difluorophenyl)-; 1-(2,4-Difluorophenyl)pyrrolidine; 524674-05-3; 2-(2,4-Difluoro-phenyl)-pyrrolidine; 2-(2,4-Difluorophenyl)azacyclopentane
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluoro-Phenyl)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, impurity profiles, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.