Description

[4-(tert-Butyl)Phenyl]Methanesulfonyl Chloride CAS NO 519056-61-2 is a specialized organosulfur reagent primarily used as a key building block in advanced organic synthesis. Its value lies in its role as a versatile sulfonylation agent, enabling the introduction of the sulfonyl chloride functional group into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of modern pesticides and herbicides, where the sulfonyl moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed to create activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	[4-(tert-Butyl)Phenyl]Methanesulfonyl Chloride
CAS No.	519056-61-2
Molecular Formula	C11H15ClO2S
Molecular Weight	246.75 g/mol
Synonyms	4-tert-Butylbenzenesulfonyl chloride; p-tert-Butylbenzenesulfonyl chloride; 1-(tert-Butyl)-4-(chlorosulfonyl)benzene; 4-(1,1-Dimethylethyl)benzenesulfonyl chloride; p-(tert-Butyl)phenylsulfonyl chloride; 4-tert-Butylphenyl methanesulfonyl chloride (common name variant); TBSC
EINECS	Contact for details

Quality Control

Our production of [4-(tert-Butyl)Phenyl]Methanesulfonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.