Description

1,4-Diiodo-2-(Trifluoromethyl)Benzene is a high-purity, multi-functional aromatic building block featuring both iodine and trifluoromethyl substituents. This compound is valued for its unique reactivity profile, enabling critical transformations in advanced chemical synthesis. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated or iodinated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and other advanced functional materials due to its electron-withdrawing characteristics.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings, leveraging the iodine atoms for selective functionalization.
• Fluorine Chemistry Research: A valuable reagent for studying the influence of the CF3 group on aromatic system reactivity and physical properties.

Basic Information

Product Name	1,4-Diiodo-2-(Trifluoromethyl)Benzene
CAS No.	518343-63-0
Molecular Formula	C7H3F3I2
Molecular Weight	421.91 g/mol
Synonyms	2-(Trifluoromethyl)-1,4-diiodobenzene; 1,4-Diiodo-2-trifluoromethylbenzene; 2-Trifluoromethyl-1,4-diiodobenzene; Benzene, 1,4-diiodo-2-(trifluoromethyl)-; α,α,α-Trifluoro-2,5-diiodotoluene
EINECS	Contact for details

Quality Control

Our 1,4-Diiodo-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.