Description

Pyridine, 4-(Trifluoromethoxy)- (9Ci) is a specialized fluorinated pyridine derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in the unique combination of the pyridine heterocycle with a trifluoromethoxy substituent, which imparts significant electronic and steric properties crucial for modulating the activity of target molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group to improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Used in organometallic chemistry to create sophisticated ligands for catalysis and materials science applications.
• Material Science Precursor: Intermediate in the synthesis of advanced organic electronic materials and liquid crystals.
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) in medicinal and agrochemical discovery programs.

Basic Information

Item	Detail
Product Name	Pyridine, 4-(Trifluoromethoxy)- (9Ci)
CAS No.	514821-10-4
Molecular Formula	C7H4F3NO
Molecular Weight	175.11 g/mol
Synonyms	4-(Trifluoromethoxy)pyridine; 4-(Trifluoromethoxyl)pyridine; 4-Pyridinyl trifluoromethyl ether; α,α,α-Trifluoro-4-pyridinyl methyl ether; 4-Trifluoromethoxypyridine; 4-(Trifluoromethoxy)pyridine (9CI); Pyridine, 4-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our Pyridine, 4-(Trifluoromethoxy)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.