Description

2-Chloro-3-Iodo-5-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring chlorine, iodine, and trifluoromethyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for developing novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of active pharmaceutical ingredients (APIs), particularly in creating molecules with improved metabolic stability and binding affinity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Functional Material Research: Serves as a starting material for synthesizing organic electronic materials, such as those used in OLEDs or semiconductors, due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to create diverse biaryl structures.

Basic Information

Product Name	2-Chloro-3-Iodo-5-(Trifluoromethyl)Pyridine
CAS No.	505084-56-0
Molecular Formula	C6H2ClF3IN
Molecular Weight	321.44 g/mol
Synonyms	2-Chloro-3-iodo-5-(trifluoromethyl)pyridine; 3-Iodo-2-chloro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-chloro-3-iodopyridine; Pyridine, 2-chloro-3-iodo-5-(trifluoromethyl)-; 2-Chloro-3-iodo-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for our halogenated pyridine intermediates. Production batches are analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.