Description

Ethyl Difluoro(6-Methoxypyridin-2-Yl)Acetate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the difluoroacetate ester group and the methoxypyridine scaffold, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Material Science Research: Used in the development of specialty chemicals, liquid crystals, and advanced polymeric materials.
• Fluorination Chemistry: Serves as a versatile reagent for introducing difluoroacetate motifs into complex molecules, a valuable transformation in medicinal chemistry.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process optimization projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	Ethyl Difluoro(6-Methoxypyridin-2-Yl)Acetate
CAS No.	503627-75-6
Molecular Formula	C10H11F2NO3
Molecular Weight	231.20 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(6-methoxypyridin-2-yl)acetate; 2-(6-Methoxy-2-pyridinyl)-2,2-difluoroacetic Acid Ethyl Ester; Difluoro(6-methoxy-2-pyridinyl)acetic Acid Ethyl Ester; Ethyl 2-(6-Methoxypyridin-2-yl)-2,2-difluoroacetate; Acetic acid, 2,2-difluoro-2-(6-methoxy-2-pyridinyl)-, ethyl ester; Ethyl α,α-Difluoro-6-methoxypicolinate
EINECS	Contact for details

Quality Control

Every batch of Ethyl Difluoro(6-Methoxypyridin-2-Yl)Acetate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.