Description

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde is a high-value, multi-functional aromatic building block that combines a formyl group with a protected boronic acid moiety. This compound is essential for facilitating efficient cross-coupling reactions, particularly in the synthesis of complex organic molecules where precise structural control is required. It is primarily sought after by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing fluorinated, boronate-substituted aromatic rings into target molecules.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where fluorinated and boronate-functionalized units modify electronic properties.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the life sciences industry.

Basic Information

Item	Details
Product Name	2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	503176-50-9
Molecular Formula	C13H16BFO3
Molecular Weight	250.08 g/mol
Synonyms	4-Formyl-3-fluorophenylboronic acid pinacol ester; 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 3-Fluoro-4-formylphenylboronic acid pinacol ester; (2-Fluoro-4-formylphenyl)boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorobenzaldehyde; 2-Fluoro-4-(pinacolatoboron)benzaldehyde; 503176-50-9; 4-Borono-2-fluorobenzaldehyde pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.