Description

2,2,2-Trifluoro-1-Pyridin-2-Yl-Ethylamine is a specialized fluorinated amine building block featuring a pyridine ring, which is of significant interest in advanced organic synthesis. This compound matters for its unique trifluoroethylamine moiety, which can dramatically alter the physicochemical properties of target molecules, enhancing metabolic stability, lipophilicity, and bioavailability. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• As a key fluorinated synthon in pharmaceutical research for creating novel drug candidates, particularly in CNS and oncology targets.
• Building block for the synthesis of advanced agrochemicals, where the fluorine atoms can improve pesticidal activity and environmental profile.
• Intermediate in the preparation of ligands and catalysts for asymmetric synthesis and cross-coupling reactions.
• Used in material science for modifying surfaces or creating fluorine-containing polymers with specific properties.
• Precursor for radiolabeling studies (e.g., with Fluorine-18) in positron emission tomography (PET) tracer development.
• Research chemical for studying structure-activity relationships (SAR) in medicinal chemistry programs.

Basic Information

Product Name	2,2,2-Trifluoro-1-Pyridin-2-Yl-Ethylamine
CAS No.	503173-14-6
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	2,2,2-Trifluoro-1-(2-pyridinyl)ethanamine; 1-(Pyridin-2-yl)-2,2,2-trifluoroethylamine; α-(Trifluoromethyl)-2-pyridineethanamine; 2,2,2-Trifluoro-1-(pyridin-2-yl)ethan-1-amine; 2-(1-Amino-2,2,2-trifluoroethyl)pyridine; 2-Pyridyl(trifluoromethyl)methylamine; 2,2,2-Trifluoro-1-(2-pyridyl)ethylamine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-Pyridin-2-Yl-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature as a fluoride/strong alkali, keep away from incompatible materials such as strong acids and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid or clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.