Description

2,6-Di-o-Butyryl-Myo-Inositol 1,3,4,5-Tetrakisphosphate-Octakis(Propionoxymethyl) Ester is a high-purity, cell-permeable derivative of inositol polyphosphate, designed for advanced biochemical and pharmacological research. This compound is a critical tool for studying intracellular signaling pathways, particularly those mediated by inositol phosphates, due to its enhanced stability and membrane permeability. It is essential for researchers and developers in pharmaceutical discovery, molecular biology, and life sciences who require reliable, high-quality probes for modulating cellular processes.

Application

• Biochemical Research: Used as a cell-permeable agonist or antagonist to study the role of inositol 1,3,4,5-tetrakisphosphate (IP4) and higher phosphorylated derivatives in calcium signaling and cellular regulation.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery and development of novel therapeutics targeting phosphoinositide signaling pathways.
• Cell Biology Studies: Employed to investigate intracellular messenger functions, including vesicle trafficking, gene expression, and neuronal communication.
• Enzymology: Acts as a substrate or inhibitor for kinases, phosphatases, and other enzymes involved in inositol phosphate metabolism.
• Signal Transduction Assays: A vital reagent in high-throughput screening (HTS) and in vitro diagnostic assays to identify modulators of specific signaling cascades.

Basic Information

Product Name	2,6-Di-o-Butyryl-Myo-Inositol 1,3,4,5-Tetrakisphosphate-Octakis(Propionoxymethyl) Ester
CAS No.	503158-20-1
Molecular Formula	C58H94O44P4
Molecular Weight	1551.23 g/mol
Synonyms	IP4-Octakis(Propionoxymethyl) Ester, 2,6-Dibutyryl-IP4-Octa-POM Ester; myo-Inositol 1,3,4,5-tetrakisphosphate, 2,6-di-O-butyryl-, octakis[(propionyloxy)methyl] ester; Cell-permeable IP4 analogue; Octa-POM-IP4; D-2,6-Di-O-butyryl-myo-inositol 1,3,4,5-tetrakisphosphate octakis(propionoxymethyl) ester; Inositol Tetrakisphosphate POM Ester; IP4 POM Ester
EINECS	Contact for details

Quality Control

Every batch of 2,6-Di-o-Butyryl-Myo-Inositol 1,3,4,5-Tetrakisphosphate-Octakis(Propionoxymethyl) Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.