Description

Odevixibat is a potent, orally administered, small-molecule ileal bile acid transporter (IBAT) inhibitor. This compound is of significant commercial and therapeutic interest for its targeted mechanism of action in treating cholestatic liver diseases. It is primarily required by pharmaceutical research organizations, contract development and manufacturing organizations (CDMOs), and fine chemical suppliers serving the global life sciences sector.

Application

• Active Pharmaceutical Ingredient (API) for the treatment of progressive familial intrahepatic cholestasis (PFIC).
• Key intermediate in the synthesis of novel IBAT inhibitors for research and development.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Biochemical research tool for studying bile acid metabolism and transport mechanisms.
• Preclinical and clinical trial material for investigating therapies for other cholestatic liver disorders.

Basic Information

Product Name	Odevixibat
CAS No.	501692-44-0
Molecular Formula	C29H35NO5S
Molecular Weight	509.66 g/mol
Synonyms	1,1-Dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N-{(R)-α-[N-((S)-1-carboxypropyl)carbamoyl]-4-hydroxybenzyl}carbamoylmethoxy)-2,3,4,5-tetrahydro-1,5-benzothiazepine; A 4250; Bylvay (trade name); A4250; Ileal Bile Acid Transporter (IBAT) Inhibitor
EINECS	Contact for details

Quality Control

Our Odevixibat is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates and reference standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15-25°C. The material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.