Description

4-Pyridinol, 2-(Difluoromethyl)- (9Ci) is a specialized fluorinated pyridine derivative, identified by CAS NO 501125-75-3. This compound is a high-value intermediate prized for its unique molecular architecture, which incorporates both a pyridine core and a difluoromethyl substituent, enabling precise modifications in advanced synthesis. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis for asymmetric synthesis.
• Material Science: Employed in the research of advanced organic electronic materials and liquid crystals due to its electron-deficient pyridine ring.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme mechanisms and protein interactions in biochemical research.

Basic Information

Product Name	4-Pyridinol, 2-(Difluoromethyl)- (9Ci)
CAS No.	501125-75-3
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2-(Difluoromethyl)pyridin-4-ol; 2-(Difluoromethyl)-4-hydroxypyridine; 4-Hydroxy-2-(difluoromethyl)pyridine; 4-Pyridinol, 2-(difluoromethyl)-; 2-Difluoromethyl-4-pyridinol
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinol, 2-(Difluoromethyl)- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, NMR, and GC-MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.