Description

(Deamino-Cys1,β-Cyclohexyl-Ala4,Arg8)-Vasopressin is a synthetic, nonapeptide analog of the endogenous hormone arginine vasopressin, engineered for enhanced receptor selectivity and metabolic stability. This compound is of significant interest for its potent and selective pharmacological profile, primarily targeting V1a and V2 vasopressin receptors. It serves as a critical research tool and active pharmaceutical ingredient (API) for advanced studies in endocrinology, cardiovascular research, and the development of novel therapeutic agents.

Application

• Pharmacological Research: A key reference standard and tool compound for investigating vasopressin receptor (V1a, V1b, V2) signaling pathways, ligand-receptor interactions, and downstream physiological effects.
• Drug Discovery & Development: Serves as a lead compound or intermediate in the development of novel therapeutics for conditions like diabetes insipidus, syndrome of inappropriate antidiuretic hormone secretion (SIADH), and cardiovascular disorders.
• Biochemical Assays: Used in high-throughput screening (HTS), competitive binding assays (e.g., radioimmunoassays), and functional assays to evaluate the potency and efficacy of new chemical entities.
• Neuroscience Studies: Employed in research exploring the role of vasopressin in social behavior, memory, stress response, and autonomic nervous system regulation.
• API Intermediate: Acts as a high-purity building block for the synthesis of more complex peptide conjugates or for formulation into preclinical and clinical study materials.

Basic Information

Product Name	(Deamino-Cys1,β-Cyclohexyl-Ala4,Arg8)-Vasopressin
CAS No.	500170-27-4
Molecular Formula	C46H68N14O12S2
Molecular Weight	1049.25 g/mol
Synonyms	d(CH2)5[D-Tyr(Et)2,Val4,Arg8]VP; Desmopressin analog; [1-Deamino-4-cyclohexylalanine, 8-arginine]vasopressin; β-cyclohexyl-Ala4-Arg8-vasopressin; V1a/V2 vasopressin receptor agonist analog; SK&F 101926; (1-β-Mercaptopropionic acid, 4-β-cyclohexylalanine, 8-arginine)vasopressin
EINECS	Contact for details

Quality Control

Our (Deamino-Cys1,β-Cyclohexyl-Ala4,Arg8)-Vasopressin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with relevant standards for research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.