Description

2-Bromo-3-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the toluene ring, which enables selective functionalization and the introduction of unique physicochemical properties into target molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring fluorinated or brominated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings to form biaryl structures.
• Fluorine Chemistry Studies: Employed in academic and industrial R&D to study the effects of fluorine substitution on aromatic systems and reaction pathways.
• Specialty Polymer Modifier: Can be incorporated into polymer chains to alter thermal stability, solubility, and other material properties.

Basic Information

Product Name	2-Bromo-3-Fluorotoluene
CAS No.	59907-13-0
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	1-Bromo-2-fluoro-3-methylbenzene; 3-Methyl-2-fluorobromobenzene; 2-Fluoro-3-methylbromobenzene; 2-Bromo-3-fluoro-1-methylbenzene; o-Bromo-m-fluorotoluene; Toluene, 2-bromo-3-fluoro-; 3-Fluoro-2-bromotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical properties. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.