Description

3-Bromo-2-Fluorotoluene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the toluene ring, makes it a versatile intermediate for introducing specific steric and electronic properties into target molecules. This compound is critically important for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in medicinal chemistry for creating fluorinated and brominated bioactive compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the halogen atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its ability to modify molecular polarity and intermolecular interactions.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings, enabling complex molecular architecture construction.
• Fluorine Chemistry Studies: An important reagent for investigating the ortho-directing influence of fluorine in electrophilic aromatic substitution and other fundamental reactions.
• Chemical Intermediate for Dyes & Pigments: Used in the synthesis of specialized halogenated dyes and functional colorants.

Basic Information

Product Name	3-Bromo-2-Fluorotoluene
CAS No.	59907-12-9
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	1-Bromo-2-fluoro-3-methylbenzene; 2-Fluoro-3-bromotoluene; 3-Methyl-2-fluorobromobenzene; Toluene, 3-bromo-2-fluoro-; o-Fluoro-m-bromotoluene; 3-Bromo-2-fluoro-1-methylbenzene; 2-Fluoro-3-methylbromobenzene
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, impurity profiles, and physical properties. Our quality commitment ensures batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.55 g/cm³
Boiling Point	~195-200 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.