Description

15(R)-Prostaglandin D2 is a specialized stereoisomer of the bioactive lipid mediator Prostaglandin D2. This compound is of significant interest in advanced biochemical and pharmacological research due to its distinct biological activity profile compared to its 15(S) counterpart. It serves as a critical reference standard and research tool for scientists investigating inflammation, allergy, and neurological pathways. Primary users include pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents.

Application

• Biochemical Research: Used as a reference standard in studies of prostanoid receptors (e.g., DP1, DP2/CRTH2) and their signaling pathways.
• Pharmacological Development: Serves as a key intermediate or active compound in the development of novel anti-inflammatory and anti-allergy therapeutics.
• Cell Signaling Studies: Employed to investigate the role of specific prostaglandin isomers in cellular processes like apoptosis, sleep regulation, and immune response.
• Analytical Standard: Essential for the calibration of analytical equipment (HPLC, LC-MS) and for method development in bioanalytical laboratories.
• Metabolite Synthesis: Acts as a precursor in the synthesis of downstream prostaglandin metabolites for metabolic pathway analysis.

Basic Information

Product Name	15(R)-Prostaglandin D2
CAS No.	59894-05-2
Molecular Formula	C20H32O5
Molecular Weight	352.47 g/mol
Synonyms	15(R)-PGD2; (5Z,13E,15R)-(15S)-9α,11α-15-Trihydroxyprosta-5,13-dien-1-oic Acid; 15R-PGD2; 15-epi-Prostaglandin D2; (15R)-Prostaglandin D2; 15R-Prostaglandin D2; PGD2 (15R-isomer)
EINECS	Contact for details

Quality Control

Our 15(R)-Prostaglandin D2 is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers should be sealed under vacuum or nitrogen after each use and allowed to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.