Description

16,16-Dimethyl Prostaglandin F2Beta is a synthetic analog of prostaglandin F2α, characterized by its enhanced metabolic stability due to the dimethyl substitution at the 16-position. This compound is of significant value in biochemical and pharmaceutical research for its potent and selective biological activity. It is primarily needed by researchers and developers in the life sciences sector, particularly those focused on ophthalmology, reproductive biology, and smooth muscle physiology.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics, particularly for glaucoma and ocular hypertension.
• Biochemical Studies: Used as a potent research tool to study prostaglandin receptors (FP receptors), signal transduction pathways, and cellular responses in various in vitro and ex vivo models.
• Ophthalmology Research: Investigation of intraocular pressure (IOP) regulation and the development of next-generation prostaglandin-based treatments for eye diseases.
• Reproductive Biology: Study of luteolysis and the role of prostaglandins in reproductive processes and fertility management.
• Smooth Muscle Physiology: Research on the contraction and relaxation mechanisms of vascular, bronchial, and uterine smooth muscle tissue.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing and regulatory testing.

Basic Information

Product Name	16,16-Dimethyl Prostaglandin F2Beta
CAS No.	59769-89-0
Molecular Formula	C22H38O5
Molecular Weight	382.54 g/mol
Synonyms	16,16-Dimethyl PGF2β; 16,16-Dimethylprostaglandin F2β; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-16,16-dimethylprosta-5,13-dien-1-oic Acid; 16,16-Dimethyl Prostaglandin F2 β; DM-PGF2β; 16,16-Dimethylprosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)-; Prostaglandin F2β, 16,16-dimethyl-
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl Prostaglandin F2Beta is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.