Description

5-tert-Butyl-1H-1,2,4-Triazole-3-Sulfonyl Chloride is a high-value sulfonyl chloride derivative of a substituted triazole, serving as a critical building block in advanced organic synthesis. This compound is prized for its reactivity as an electrophilic sulfonylation agent, enabling the introduction of the sulfonamide functional group into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Building block for functional polymers and advanced materials requiring specific sulfonamide linkages.
• Chemical Biology: Employed in the development of activity-based probes and bioconjugation reagents for protein labeling.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API development.
• Research & Development: Essential reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-tert-Butyl-1H-1,2,4-Triazole-3-Sulfonyl Chloride
CAS No.	59689-65-5
Molecular Formula	C₆H₁₀ClN₃O₂S
Molecular Weight	223.68 g/mol
Synonyms	5-tert-Butyl-1,2,4-triazole-3-sulfonyl chloride; 5-(tert-Butyl)-1H-1,2,4-triazole-3-sulfonyl chloride; 3-(tert-Butyl)-1H-1,2,4-triazole-5-sulfonyl chloride; 1H-1,2,4-Triazole-3-sulfonyl chloride, 5-(1,1-dimethylethyl)-; tert-Butyl-1,2,4-triazole sulfonyl chloride; TBTS-Cl
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-1H-1,2,4-Triazole-3-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.