Description

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-(2-Phenoxymethyl-1,3-Dioxolan-2-Yl)Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester is a high-purity synthetic prostaglandin intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex, biologically active molecules targeting specific therapeutic pathways. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and fine chemical industries for the production of novel drug candidates.

Application

• Key Intermediate in Prostaglandin Synthesis: Acts as a crucial precursor in the multi-step synthesis of prostaglandin analogs and related eicosanoids.
• Pharmaceutical R&D: Used in medicinal chemistry programs for the development of new therapeutic agents targeting inflammation, cardiovascular function, and reproductive health.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized as a reference standard or tool compound in studies investigating prostaglandin receptor interactions and signaling pathways.
• Fine Chemical Manufacturing: Serves as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-(2-Phenoxymethyl-1,3-Dioxolan-2-Yl)Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester
CAS No.	59619-78-2
Molecular Formula	C25H34O7
Molecular Weight	446.53 g/mol
Synonyms	Methyl (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-(2-phenoxymethyl-1,3-dioxolan-2-yl)prop-1-enyl]cyclopentyl]hept-5-enoate; Prostaglandin F2α Methyl Ester Dioxolane Derivative; 9,11,15-Trihydroxy-16-phenoxymethyl-17,18,19,20-tetranorprosta-5,13-dien-1-oic Acid Methyl Ester Cyclic Acetal; 16-Phenoxymethyl PGF2α Methyl Ester Cyclic Acetal; 59619-78-2; PGF2α Analogue Intermediate; 16-(Phenoxymethyl)-9,11,15-trihydroxy-17,18,19,20-tetranorprosta-5,13-dien-1-oic Acid Methyl Ester Cyclic Ketal
EINECS	Contact for details

Quality Control

Our (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-(2-Phenoxymethyl-1,3-Dioxolan-2-Yl)Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements. We support development with GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.