Description

1-Chloro Methane Sulfonyl Bromide is a highly reactive organosulfur compound primarily used as a versatile sulfonylation and sulfamoylation reagent in advanced organic synthesis. Its value lies in its ability to introduce the chloromethanesulfonyl functional group, a key building block for creating complex molecules with specific biological or material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to create novel sulfonylurea or sulfonamide herbicides and pesticides with enhanced efficacy.
• Material Science: Employed in the production of specialty polymers, functionalized surfaces, and advanced electrolytes for battery applications.
• Chemical Research: A crucial reagent for introducing the chloromethanesulfonyl moiety in medicinal chemistry and process development labs.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	1-Chloro Methane Sulfonyl Bromide
CAS No.	59059-72-2
Molecular Formula	C2H4BrClO2S
Molecular Weight	207.47 g/mol
Synonyms	Chloromethanesulfonyl Bromide; Methanesulfonyl Chloride Bromide; Bromo(chloromethanesulfonyl); 1-Chloro-1-methanesulfonyl Bromide; (Chlorosulfonyl)methyl Bromide; CMSB; α-Bromo-α-chloromethanesulfonic acid (related form)
EINECS	Contact for details

Quality Control

Our 1-Chloro Methane Sulfonyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.