Description

17-Phenyl Trinor Prostaglandin F2α-D4 is a deuterium-labeled analog of a key prostaglandin metabolite, serving as a critical internal standard for precise analytical quantification. This high-purity compound is essential for ensuring accuracy and reliability in sensitive bioanalytical methods, particularly liquid chromatography-mass spectrometry (LC-MS). It is primarily utilized by research institutions, pharmaceutical developers, and contract research organizations (CROs) engaged in metabolic studies, drug development, and clinical research requiring the highest level of analytical fidelity.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a deuterated internal standard for the accurate quantification of prostaglandin F2α and its metabolites in complex biological matrices like plasma, serum, and urine.
• Biomarker Research: Facilitates research into inflammatory pathways, reproductive biology, and other physiological processes where prostaglandins serve as key signaling molecules.
• Drug Metabolism and Pharmacokinetics (DMPK): Critical in pharmaceutical R&D for studying the pharmacokinetic profile and metabolic fate of drug candidates affecting the arachidonic acid pathway.
• Clinical Diagnostics Development: Supports the development and validation of robust clinical assays for measuring prostaglandin levels as potential disease biomarkers.
• Quality Control in Reference Material Production: Employed in the calibration and verification of assay performance for prostaglandin-related testing kits and certified reference materials.

Basic Information

Product Name	17-Phenyl Trinor Prostaglandin F2α-D4
CAS No.	58976-50-4
Molecular Formula	C₂₃H₂₈D₄O₅
Molecular Weight	392.52 g/mol
Synonyms	17-Phenyl-13,14-dihydro-trinor Prostaglandin F2α-d4; 9α,11α,15-Trihydroxy-17-phenyl-18,19,20,20-tetradeutero-prost-13-en-1-oic Acid; PGF2α-17-phenyl trinor-d4; Deuterated 17-Phenyl PGF2α; 17-Phenyl-trinor-PGF2α-d4; 17-Phenyl-13,14-dihydro-PGF2α-d4; 9α,11α,15-Trihydroxy-17-phenyl-18,19,20,20-d4-prost-13-enoic Acid
EINECS	Contact for details

Quality Control

Every batch of 17-Phenyl Trinor Prostaglandin F2α-D4 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, confirmed by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and chromatographic data is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.