Description

13,14-Dihydroprostaglandin E1 is a key synthetic prostaglandin analog and a derivative of the naturally occurring prostaglandin E1 (PGE1). This compound is valued for its enhanced metabolic stability compared to its parent molecule, making it a crucial intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on cardiovascular, inflammatory, and reproductive health therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel prostaglandin-based drugs targeting vasodilation and platelet aggregation inhibition.
• Biochemical Research: Used as a reference standard and active agent in studies investigating prostaglandin receptor (EP) signaling pathways and their physiological roles.
• Cardiovascular Research: Applied in preclinical models to study the effects of prostaglandin analogs on vascular tone, blood flow, and endothelial function.
• Anti-inflammatory Studies: Investigated for its potential modulatory effects on inflammatory mediators and processes in cellular and animal models.
• Drug Metabolism & Pharmacokinetics (DMPK): Employed as a stable analog to study the metabolic fate and stability profiles of prostaglandin therapeutics.

Basic Information

Product Name	13,14-Dihydroprostaglandin E1
CAS No.	58962-34-8
Molecular Formula	C20H34O5
Molecular Weight	354.48 g/mol
Synonyms	13,14-Dihydro PGE1; DH-PGE1; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 13,14-Dihydroprostaglandin E1; 13,14-Dihydro-PGE1; 9-Oxo-11α,15-dihydroxy-13,14-dihydroprosta-5,13-dien-1-oic Acid; Prostaglandin E1, 13,14-dihydro-
EINECS	Contact for details

Quality Control

Our 13,14-Dihydroprostaglandin E1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.