Description

Lonomycin is a potent polyether antibiotic belonging to the ionophore class, known for its ability to transport ions across biological membranes. This compound is crucial for research and development in microbiology and veterinary medicine, serving as a valuable tool for studying ion transport mechanisms and bacterial growth inhibition. It is primarily utilized by pharmaceutical researchers, academic institutions, and manufacturers in the animal health sector for developing novel therapeutic agents and feed additives.

Application

• Pharmaceutical Research: Used as a reference standard and active pharmaceutical ingredient (API) in antimicrobial research and drug discovery programs.
• Veterinary Medicine: Employed in the development of coccidiostats and growth promoters for livestock and poultry.
• Microbiological Studies: Serves as a selective agent in cell culture and microbiology to study ionophore activity and membrane transport.
• Biochemical Research: Utilized as a probe to investigate calcium and other cation fluxes in cellular processes.
• Feed Additive Precursor: Acts as a key intermediate in the synthesis of specialized animal nutrition products.

Basic Information

Product Name	Lonomycin
CAS No.	58785-63-0
Molecular Formula	C₃₄H₆₂O₈
Molecular Weight	598.86 g/mol
Synonyms	Lonomycin A; Lasalocid E; Antibiotic X-537A; Lonomycin sodium salt; Lonomycin free acid; Ro 21-6150; Ionophore X-537A; 6-[6-[5-Ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxohexyl]-2-hydroxy-3-methylbenzoic acid δ-lactone
EINECS	Contact for details

Quality Control

Our Lonomycin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.