Description

4-Chlorosulfonylimidazole is a versatile and highly reactive sulfonyl chloride derivative of imidazole, serving as a critical building block in advanced organic synthesis. Its unique structure enables the efficient introduction of the imidazole-sulfonyl moiety, making it indispensable for creating complex molecules with tailored properties. This intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Functional Material Development: Building block for polymers and ligands used in catalysis and material science.
• Bioconjugation Chemistry: Reactive handle for modifying proteins, peptides, and other biomolecules in research.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific projects.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new heterocyclic compounds and reaction pathways.

Basic Information

Product Name	4-Chlorosulfonylimidazole
CAS No.	58767-51-4
Molecular Formula	C3H3ClN2O2S
Molecular Weight	166.58 g/mol
Synonyms	1H-Imidazole-4-sulfonyl chloride; Imidazole-4-sulfonyl chloride; 4-Imidazolesulfonyl chloride; 1H-Imidazole-4-sulfonoyl chloride; 4-(Chlorosulfonyl)-1H-imidazole; 4-Sulfonylchloride imidazole
EINECS	Contact for details

Quality Control

Our 4-Chlorosulfonylimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.