Description

N,n-Dimethylmuscimol is a synthetic derivative of the naturally occurring neuroactive compound muscimol, featuring dimethyl substitution on the nitrogen. This structural modification is of significant interest in neuroscience research and medicinal chemistry for studying and modulating GABAA receptor subtypes. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in central nervous system drug discovery and neuropharmacology.

Application

• Neuroscience Research: A key pharmacological tool for investigating the structure-activity relationships and functional roles of specific GABAA receptor isoforms.
• Drug Discovery Programs: Serves as a reference compound or synthetic intermediate in the development of novel neurotherapeutics targeting anxiety, epilepsy, and sleep disorders.
• Biochemical Assay Development: Used in in vitro binding and functional assays to screen and characterize new chemical entities for GABAergic activity.
• Metabolic Pathway Studies: Employed in research to understand the metabolism and pharmacokinetics of muscimol analogs.
• Academic & Clinical Research: Supports fundamental studies on neurotransmission, synaptic plasticity, and the etiology of neurological conditions.

Basic Information

Product Name	N,n-Dimethylmuscimol
CAS No.	58728-65-7
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	5-(Dimethylaminomethyl)-3-hydroxyisoxazole; 3-Hydroxy-5-[(dimethylamino)methyl]-1,2-oxazole; Dimethylmuscimol; 5-[(Dimethylamino)methyl]-3-isoxazolol; 5-(Dimethylaminomethyl)-3-isoxazolol; GABAA receptor research compound
EINECS	Contact for details

Quality Control

Our N,n-Dimethylmuscimol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider keeping the product under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.