Description

Rac-11-Epi-Misoprostol is a synthetic prostaglandin E1 (PGE1) analogue, specifically a stereoisomer of the well-known pharmaceutical compound misoprostol. This compound is of significant value in pharmaceutical research and development, particularly for studying structure-activity relationships and the biological effects of specific stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of prostaglandin-based therapeutics, analytical method development, and as a reference standard for quality control.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for the identification, purity assessment, and quantification of misoprostol and related compounds in analytical laboratories.
• Research & Development: Used as a key intermediate or analytical tool in medicinal chemistry programs focused on prostaglandin analogues, helping to elucidate the impact of stereochemistry on biological activity.
• Metabolite Studies: Employed in pharmacological and toxicological research to investigate the metabolic pathways and stability of prostaglandin derivatives.
• Process Chemistry: Acts as a process-related impurity standard in the manufacturing and quality control of misoprostol Active Pharmaceutical Ingredients (APIs), ensuring product purity and regulatory compliance.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis, stereochemistry, and prostaglandin biology.

Basic Information

Product Name	Rac-11-Epi-Misoprostol
CAS No.	58717-36-5
Molecular Formula	C22H38O5
Molecular Weight	382.54 g/mol
Synonyms	(±)-11-Epi-misoprostol; rac-11-Epimisoprostol; 11-Epi-misoprostol (racemic); SC-31611 (epimer); (11R,16S)-11,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester (racemate); Methyl (1R,2R,3R)-3-hydroxy-2-[(1E,4R)-4-hydroxy-4-methyl-1-octen-1-yl]-5-oxocyclopentaneheptanoate (racemic mixture); Prostaglandin E1 analogue.
EINECS	Contact for details

Quality Control

Our Rac-11-Epi-Misoprostol is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets high-purity standards suitable for research and reference applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.