Description

Carboprost Tromethamine is a synthetic prostaglandin analog of the F2α series, formulated as a stable tromethamine salt. This compound is critically important for its potent uterotonic and luteolytic properties, making it a key active pharmaceutical ingredient (API) in specialized therapeutic applications. It is primarily required by pharmaceutical manufacturers and research institutions focused on developing and producing advanced obstetric and gynecological medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the management of postpartum hemorrhage (PPH) due to uterine atony.
• Therapeutic Abortion: Used in medical procedures for pregnancy termination during the second trimester.
• Veterinary Medicine: Employed in large animal reproduction for estrus synchronization and the treatment of conditions like pyometra in cattle.
• Biochemical Research: Serves as a critical reference standard and tool compound in prostaglandin receptor (FP receptor) studies and reproductive biology research.
• Drug Development: Used in the formulation and stability testing of new parenteral drug products targeting uterine and cervical tissues.

Basic Information

Product Name	Carboprost Tromethamine
CAS No.	58551-69-2
Molecular Formula	C₂₅H₄₇NO₈ • C₄H₁₁NO₃
Molecular Weight	489.63 g/mol (as free acid); Tromethamine salt MW: Contact for details
Synonyms	Carboprost Trometamol; (15S)-15-Methylprostaglandin F2α Tromethamine Salt; U-36,473F; Hemabate (Brand Name); Prostin/15M (Brand Name); 7-[3,5-Dihydroxy-2-[(3S)-3-hydroxy-3-methyloct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol; 15(S)-15-Methyl PGF2α Tromethamine
EINECS	Contact for details

Quality Control

Our Carboprost Tromethamine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results against relevant standards is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store unopened vials at a controlled room temperature of 15-25°C or under refrigeration at 2-8°C as specified. This product is easily oxidized; for long-term storage, maintaining an inert atmosphere (e.g., under nitrogen or argon) is recommended. Keep the container dry and in a well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.