Description

Ethyl(1-Acetoxyethyl)Nitrosamine is a specialized nitrosamine compound of significant interest in chemical research and development. This compound serves as a critical intermediate and reference standard in analytical chemistry, particularly for method development and validation. It is primarily utilized by research institutions and quality control laboratories in the pharmaceutical, agrochemical, and advanced materials sectors for trace analysis and impurity profiling studies.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and validation of testing methods for nitrosamine detection.
• Pharmaceutical Impurity Profiling: Critical for developing and validating sensitive analytical methods (e.g., LC-MS/MS, GC-MS) to detect and quantify nitrosamine impurities in active pharmaceutical ingredients (APIs) and finished drug products, ensuring compliance with stringent regulatory guidelines (e.g., FDA, EMA).
• Chemical Research Intermediate: Employed in synthetic organic chemistry research for studying nitrosation reactions and the synthesis of more complex molecules.
• Toxicological Studies: Serves as a standard compound in metabolic and genotoxicity research to understand the biological impact of nitrosamine exposure.
• Quality Control & Assurance: Essential for in-house method qualification and ongoing quality control in laboratories requiring high-purity analytical standards.
• Regulatory Compliance Testing: Supports compliance testing for industries regulated for nitrosamine content, including certain polymers, rubber chemicals, and food contact materials.

Basic Information

Product Name	Ethyl(1-Acetoxyethyl)Nitrosamine
CAS No.	58431-24-6
Molecular Formula	C6H12N2O3
Molecular Weight	160.17 g/mol
Synonyms	N-Nitroso-N-ethyl-2-acetoxyethylamine; N-Ethyl-N-(2-acetoxyethyl)nitrosamine; 2-(Ethylnitrosamino)ethyl acetate; NEAA; N-Nitrosoethyl(2-acetoxyethyl)amine; Acetoxyethyl ethyl nitrosamine; 1-Acetoxy-2-(ethylnitrosamino)ethane
EINECS	Contact for details

Quality Control

Our Ethyl(1-Acetoxyethyl)Nitrosamine is manufactured and handled under strict quality management protocols. Each batch undergoes rigorous identity confirmation and purity analysis using advanced techniques such as HPLC, GC-MS, and NMR spectroscopy to ensure it meets the high standards required for analytical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). For long-term stability, consider storage under inert atmosphere. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (by HPLC)	≥ 95.0%
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Report and comply with customer requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.