Description

Oxytocin, Hydroxy-Thr(4)- CAS NO 58418-35-2 is a synthetic analogue of the neuropeptide hormone oxytocin, specifically modified at the fourth position with a hydroxy-threonine residue. This modification is of significant interest for enhancing the stability, receptor selectivity, and pharmacokinetic profile of the peptide for advanced research and development. It is a critical compound for pharmaceutical researchers, biochemists, and manufacturers focused on neuroendocrinology, peptide therapeutics, and drug discovery programs.

Application

• Pharmaceutical Research & Development: As a key reference standard and active ingredient in the development of novel oxytocin-based therapeutics for conditions like social disorders, autism spectrum disorders, and postpartum depression.
• Neurobiological Studies: Used in in vitro and in vivo studies to investigate the role of oxytocin receptors in social bonding, stress response, and maternal behavior.
• Peptide Chemistry & Structure-Activity Relationship (SAR) Studies: Serves as a crucial building block for synthesizing and studying modified peptide sequences to understand the impact of specific amino acid substitutions on biological activity.
• Biochemical Assay Development: Employed as a high-purity ligand in competitive binding assays, receptor activation tests, and high-throughput screening (HTS) platforms.
• Veterinary Medicine Research: Investigated for applications in animal behavior, reproduction, and stress management in livestock and companion animals.
• Academic Research: Essential for university and institutional labs conducting cutting-edge research in endocrinology, pharmacology, and behavioral science.

Basic Information

Product Name	Oxytocin, Hydroxy-Thr(4)- CAS NO 58418-35-2
CAS No.	58418-35-2
Molecular Formula	C₄₃H₆₆N₁₂O₁₂S₂
Molecular Weight	1007.2 g/mol
Synonyms	4-Threonine-oxytocin; Hydroxy-Thr(4)-Oxytocin; [Thr4, Gly7]-Oxytocin; Oxytocin (4-Thr); 1-{(4R,7S,10S,13S,16S,19R)-19-Amino-13-benzyl-10-(2-amino-2-oxoethyl)-7,16-bis(3-amino-3-oxopropyl)-4-[(1R)-1-carboxy-2-(methylsulfanyl)ethyl]-3,6,9,12,15,18-hexaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-22-yl}-2-amino-3-hydroxybutanoic acid
EINECS	Contact for details

Quality Control

Our Oxytocin, Hydroxy-Thr(4)- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications. Our quality commitment supports your need for reliable and consistent peptide materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.