Description

2-(4-(Trifluoromethyl)Phenylamino)Isonicotinonitrile is a specialized heterocyclic organic compound featuring a trifluoromethylphenylamino substituent. This molecule is valued for its unique structural motif, which combines a pyridine core with an aniline derivative, making it a versatile intermediate in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Serves as a precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl and cyano groups.
• Material Science: Used in the synthesis of advanced organic materials, such as ligands for catalysts or monomers for specialty polymers with specific electronic properties.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition or protein-ligand interactions due to its distinct pharmacophore.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	2-(4-(Trifluoromethyl)Phenylamino)Isonicotinonitrile
CAS No.	58408-95-0
Molecular Formula	C13H8F3N3
Molecular Weight	263.22 g/mol
Synonyms	2-[(4-(Trifluoromethyl)phenyl)amino]isonicotinonitrile; 2-[(4-Trifluoromethylphenyl)amino]pyridine-4-carbonitrile; 4-Cyano-2-[(4-trifluoromethylphenyl)amino]pyridine; 2-(4-Trifluoromethyl-anilino)isonicotinonitrile; N-(4-Trifluoromethylphenyl)pyridine-2,4-diamine-4-carbonitrile; 2-Amino-6-(4-trifluoromethylphenylamino)nicotinonitrile (isomer); 58408-95-0
EINECS	Contact for details

Quality Control

Our 2-(4-(Trifluoromethyl)Phenylamino)Isonicotinonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.