Description

Diphenylethanone Impurity 1 is a high-purity chemical reference standard used for analytical and research purposes. This compound is critical for ensuring the quality, safety, and regulatory compliance of pharmaceutical products and fine chemicals. It is primarily utilized by analytical chemists, quality control laboratories, and research scientists in the pharmaceutical and chemical development sectors for method validation and impurity profiling.

Application

• Pharmaceutical Impurity Profiling: Serves as a certified reference material for the identification and quantification of related substances in Diphenylethanone (Benzil) and its derivative APIs.
• Analytical Method Development: Used as a standard to develop and validate HPLC, GC, and other chromatographic methods for purity analysis.
• Quality Control & Assurance: Essential for in-process testing and final release testing of active pharmaceutical ingredients (APIs) to meet pharmacopeial standards (e.g., USP, EP).
• Research & Development: Employed in synthetic chemistry research to study reaction pathways, by-product formation, and degradation chemistry.
• Regulatory Compliance & Documentation: Provides necessary data for regulatory filings (e.g., FDA, EMA) to establish impurity limits and control strategies.
• Calibration Standard: Used to calibrate analytical instruments to ensure accurate and reproducible measurement of specific impurities.

Basic Information

Product Name	Diphenylethanone Impurity 1
CAS No.	58280-04-9
Molecular Formula	C14H12O2
Molecular Weight	212.24 g/mol
Synonyms	Benzil Impurity 1; 1,2-Diphenylethane-1,2-dione Impurity; Dibenzoyl Impurity; (E)-1,2-Diphenylethene-1,2-diol; Stilbene-1,2-diol; 1,2-Dihydroxy-1,2-diphenylethylene; Benzoin dehydration product; 1,2-Diphenyl-1,2-ethanediol (dehydrated form)
EINECS	Contact for details

Quality Control

Every batch of Diphenylethanone Impurity 1 is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and accurate identification, meeting the stringent requirements for reference standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.