Description

Clindamycin Hydrochloride is a semi-synthetic lincosamide antibiotic derived from lincomycin. It is a critical active pharmaceutical ingredient (API) valued for its potent activity against anaerobic bacteria and certain protozoa. This compound is essential for manufacturers in the pharmaceutical industry, particularly for the formulation of injectable and topical antibiotic preparations.

Application

• Pharmaceutical API: Primary use as the active ingredient in antibiotic formulations.
• Injectable Solutions: Manufacture of sterile injectable products for systemic bacterial infections.
• Topical Preparations: Key component in gels, lotions, and creams for treating acne vulgaris and other skin infections.
• Vaginal Applications: Used in creams and suppositories for treating bacterial vaginosis.
• Dental Applications: Employed in treatments for odontogenic infections and periodontal disease.
• Veterinary Medicine: Formulated for treating bacterial infections in animals.
• Research & Development: Serves as a reference standard and for pharmacological studies in microbiological research.

Basic Information

Product Name	Clindamycin Hydrochloride
CAS No.	58207-19-5
Molecular Formula	C18H33ClN2O5S • HCl
Molecular Weight	461.44 g/mol (as hydrochloride)
Synonyms	Clindamycin HCl; 7(S)-Chloro-7-deoxylincomycin Hydrochloride; U-28508; Dalacin C; Cleocin Hydrochloride; Clinimycin Hydrochloride; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide Hydrochloride
EINECS	261-189-6

Quality Control

Our Clindamycin Hydrochloride is manufactured under strict quality management systems. It is tested to meet relevant pharmacopoeial standards such as USP, EP, and BP for identity, purity, and potency. Comprehensive analytical testing, including HPLC for assay and related substances, is performed. A Certificate of Analysis (COA) is provided with each batch to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC, anhydrous basis)	98.0% - 102.0%
Water Content (KF)	≤ 6.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Specific Rotation	+135° to +150° (c=1 in water)
pH (1% solution)	3.0 - 5.5
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.