Description

2-Fluoro-1-Methylpyridinium p-Toluenesulfonate is a high-purity fluoropyridinium salt widely recognized as a powerful and versatile alkylating agent in organic synthesis. Its primary value lies in its ability to efficiently introduce methyl groups under mild conditions, making it a critical reagent for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced material industries, where precise methylation is required for active ingredient development and fine chemical production.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the selective O-, N-, and S-methylation in the development of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides where methylation steps are crucial for bioactivity.
• Material Science Research: Employed in the synthesis of ionic liquids, specialty polymers, and functionalized organic materials.
• Process Chemistry & Scale-up: Valued for its reactivity and selectivity in pilot plant and commercial-scale manufacturing processes.
• Academic & R&D Laboratories: A staple reagent for methodology development and the synthesis of novel organic compounds.
• Fine Chemical Production: Utilized in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	2-Fluoro-1-Methylpyridinium p-Toluenesulfonate
CAS No.	58086-67-2
Molecular Formula	C₁₄H₁₆FNO₃S
Molecular Weight	297.35 g/mol
Synonyms	1-Methyl-2-fluoropyridinium Tosylate; 2-Fluoro-1-methylpyridinium Tosylate; 2-Fluoro-N-methylpyridinium p-Toluenesulfonate; 2-Fluoro-1-methylpyridin-1-ium 4-methylbenzenesulfonate; Methyl(2-fluoropyridin-1-ium) Tosylate; FMP-TsO; 2-Fluoro-1-methylpyridinium Salt; Fluoromethylpyridinium Tosylate
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-1-Methylpyridinium p-Toluenesulfonate is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency to meet the rigorous demands of synthesis and scale-up. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with full analytical data (including HPLC/GC purity, NMR identification, and moisture content) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity and stability. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.