Description

(17S,20S)-5α-Pregnane-3β,12β,14β,17,20-Pentol 12,20-Diacetate is a high-purity, multi-functional steroid derivative with significant synthetic utility. This compound matters as a critical advanced intermediate for the research and development of novel pharmaceutical agents, particularly in the synthesis of complex bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and enzyme inhibition research.
• Fine Chemical Synthesis: Serves as a versatile chiral template for constructing complex molecular architectures in advanced organic synthesis.
• Academic & Contract Research: Employed in university and CRO settings for methodological development in steroid chemistry and medicinal chemistry projects.
• Process Development: Utilized in scaling up synthetic routes for potential drug candidates during preclinical and early development phases.

Basic Information

Product Name	(17S,20S)-5α-Pregnane-3β,12β,14β,17,20-Pentol 12,20-Diacetate
CAS No.	57943-41-6
Molecular Formula	C₂₅H₄₀O₇
Molecular Weight	452.58 g/mol
Synonyms	3β,12β,14β,17,20-Pentahydroxy-5α-pregnan-12,20-diacetate; 12β,20-Diacetoxy-5α-pregnane-3β,14β,17-triol; 5α-Pregnane-3β,12β,14β,17,20-pentol 12,20-diacetate; (17S,20S)-12β,20-Diacetoxy-5α-pregnane-3β,14β,17-triol; 3β,14β,17-Trihydroxy-12β,20-diacetoxy-5α-pregnane; Pregnane pentol diacetate derivative
EINECS	Contact for details

Quality Control

Our (17S,20S)-5α-Pregnane-3β,12β,14β,17,20-Pentol 12,20-Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.