Description

16,16-Dimethyl-Delta(4)-Prostaglandin F1Alpha is a synthetic analog of prostaglandin F1α, characterized by its modified structure which enhances stability and biological activity. This compound is a critical intermediate and research tool in the development of novel pharmaceuticals, particularly in the fields of ophthalmology and reproductive medicine. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-characterized prostaglandin derivatives for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced prostaglandin-based therapeutics.
• Ophthalmic Research: Used in studies related to intraocular pressure and the development of treatments for conditions like glaucoma.
• Reproductive Health Research: Applied in biochemical research concerning uterine contraction and fertility studies.
• Cell Signaling Studies: Utilized as a tool compound to investigate FP receptor pathways and related cellular processes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.

Basic Information

Product Name	16,16-Dimethyl-Delta(4)-Prostaglandin F1Alpha
CAS No.	57931-23-4
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	16,16-Dimethyl-PGF1α; 16,16-Dimethyl-δ4-PGF1α; 9,11,15-Trihydroxy-16,16-dimethyl-5,13-prostadienoic acid; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-16,16-dimethyl-5,13-prostadienoic acid; 16,16-Dimethylprostaglandin F1α; DM-PGF1α; Prostaglandin F1α analog
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl-Delta(4)-Prostaglandin F1Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.