Description

Ibazocine is a potent and selective κ-opioid receptor (KOR) agonist, a key pharmacological tool compound for neuroscience research. Its primary value lies in its ability to help researchers study the complex physiological and behavioral effects mediated by the κ-opioid receptor system. This makes it an essential chemical for pharmaceutical R&D, academic institutions, and contract research organizations focused on pain management, addiction, mood disorders, and neuropsychiatric research. We supply high-purity Ibazocine CAS NO 57653-28-8 to support critical, reproducible scientific discovery.

Application

• Neuroscience Research: A standard tool for investigating the role of κ-opioid receptors in the central nervous system.
• Pharmacological Studies: Used in in vitro and in vivo assays to characterize receptor binding, selectivity, and signal transduction pathways.
• Pain Mechanism Research: Employed to study the complex, often dualistic (pro- and anti-nociceptive), role of KOR agonists in pain perception.
• Psychiatric Disorder Models: Utilized in preclinical research related to depression, anxiety, stress responses, and drug addiction mechanisms.
• Drug Discovery & Development: Serves as a reference compound for screening and developing novel analgesics and neuropsychiatric therapeutics with reduced side-effect profiles.
• Academic & Institutional Labs: Supplied to universities and research institutes for fundamental neuropharmacology studies and educational purposes.

Basic Information

Product Name	Ibazocine
CAS No.	57653-28-8
Molecular Formula	C19H25NO2
Molecular Weight	299.41 g/mol
Synonyms	Ibazocine; (-)-Ibazocine; (5R,9R,13S,14S)-3-Allyl-4,5-epoxy-6,14-ethano-6,7,8,14-tetrahydro-4H-benzofuro[3,2-e]isoquinoline-5,9,13-triol; 3-Allyl-4,5α-epoxy-6,14-ethano-6,7,8,14-tetrahydro-4H-benzofuro[3,2-e]isoquinoline-5α,9,13-triol; κ-opioid receptor agonist; KOR agonist
EINECS	Contact for details

Quality Control

Our Ibazocine is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to high standards suitable for research and development use, with specifications tailored to meet the rigorous demands of pharmacological and biochemical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.